The primary goal of the national infertility prevention program is to provide routine screening and treatment services in family planning and sexually transmitted disease (STD) clinics for Chlamydia trachomatis infection. The program is based on the premise that timely treatment for Chlamydia trachomatis can reduce the debilitating complications caused by this sexually transmitted disease, including pelvic inflammatory disease (PID), ectopic pregnancy, and infertility. The project was legislated under the name of Infertility Prevention Program and is a result of a collaborative agreement between the Office of Population Affairs (OPA) and the Centers for Disease Control and Prevention (CDC).

In Region I (6 New England states), the regional advisory committee has been created to develop guidelines and standards to assess and reduce the prevalence of Chlamydia trachomatis in the region. The advisory committee is comprised of regional representatives from Title X family planning agencies, STD programs, and public health laboratories. Region I has developed a regional plan that outlines the specific activities to be undertaken to control chlamydia and chlamydia-related sequelae in the region. The advisory committee's primary role is to oversee and approve project activities.

John Snow, Inc. (JSI), is responsible for managing the project. Specifically, JSI is responsible for the coordination of regular advisory committee meetings, which include subcommittee work. JSI also provides technical guidance to the participating programs on the collection and maintenance of data, the development of quality assurance systems and project service protocols. JSI is also responsible for the evaluation of regional data, coordinates training activities associated with this project and provides technical support to the state programs participating in this regional project.